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National Chung Hsing University Institutional Repository - NCHUIR > 農業暨自然資源學院 > 生物產業機電工程學系 > 依資料類型分類 > 期刊論文 >  Effect of polydimethylsiloxane surfaces silanized with different nitrogen-containing groups on the adhesion progress of epithelial cells

Please use this identifier to cite or link to this item: http://nchuir.lib.nchu.edu.tw/handle/309270000/125960

標題: Effect of polydimethylsiloxane surfaces silanized with different nitrogen-containing groups on the adhesion progress of epithelial cells
作者: Wu, Ching-Chou;Yuan, Chia-Yin;Ding, Shinn-Jyh
Contributors: 國立中興大學生物產業機電工程學系
National Chung Hsing University,Department of Bio-industrial Mechatronics Engineering
Miao-zhen Luo
關鍵字: Polydimethylsiloxane;Surface modification;Oxygen plasma;Silanization;Cell adhesion;self-assembled monolayers;protein adsorption;hydrophobic recovery;functional-groups;polymer surfaces;silicone rubbers;oxygen plasma;poly(dimethylsiloxane);pdms;attachment
日期: 2011-2
Issue Date: 2012-10-19 14:23:52 (UTC+8)
摘要: There have been few studies on the effect of the grafting of nitrogen-containing functional groups on polydimethylsiloxane (PDMS) surfaces and, in particular, the CN bond, on cell adhesion to the surfaces. In this study, two different silanes, one containing an amine group [(3-aminopropyl)trimethoxysilane; APTMS] and the other a nitrile group [(3-cyanopropyl)triethoxysilane; CPTES], were adopted to modify PDMS following oxygen plasma treatment. The effects of surface modification on the density of HeLa and MDCK cells were evaluated, in addition to the measurement of the contact angle with the surface and the chemical composition. The results indicated that the CPTES modification allowed the PDMS surface to have better hydrophilicity than the APTMS modification. Nitrogen-containing functionalities were more beneficial for cell spreading, in comparison with the pristine and oxygen plasma-treated PDMS. The present method of APTMS and CPTES grafting provides a simple and efficient method for promoting cell adhesion on PDMS. Crown Copyright (C) 2010 Published by Elsevier B.V. All rights reserved.
Relation: Surface & Coatings Technology, Volume 205, Issue 10, Page(s) 3182-3189.
Appears in Collections:[依資料類型分類] 期刊論文

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