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National Chung Hsing University Institutional Repository - NCHUIR > 中興大學 > 期刊論文 >  A 10-year Follow-up of Triple-negative Breast Cancer Patients in Taiwan

Please use this identifier to cite or link to this item: http://nchuir.lib.nchu.edu.tw/handle/309270000/138373

標題: A 10-year Follow-up of Triple-negative Breast Cancer Patients in Taiwan
作者: Lin, C.;Chien, S.Y.;Kuo, S.J.;Chen, L.S.;Chen, S.T.;Lai, H.W.;Chang, T.W.;Chen, D.R.
關鍵字: triple-negative breast cancer;HER2;estrogen receptor;progesterone;receptor;survival;international expert consensus;long-term survival;estrogen-receptor;prognostic-factor;primary therapy;carcinoma;subtype;metastasis;highlights;recurrence
日期: 2012
Issue Date: 2012-12-14 14:54:12 (UTC+8)
關連: Japanese Journal of Clinical Oncology, Volume 42, Issue 3, Page(s) 161-167.
摘要: This study aimed to investigate whether triple-negative breast cancer has a worse prognosis; here, we present the 10-year follow-up results of triple-negative breast cancer patients in Taiwan. We identified 2858 breast cancer patients in Taiwan, of whom 416 (14.6) had triple-negative breast cancer. Data used for analysis were derived from those breast cancer patients who were diagnosed between January 1996 and December 2006. In the KaplanMeier analysis, tumor subgroup (triple-negative breast cancer vs. non-triple-negative breast cancer) was a prognostic factor related to 10-year breast cancer death-specific survival and disease-free survival. The results of univariate analysis showed that tumor subgroup was a significant factor related to 10-year disease-free survival and breast cancer death-specific survival, as well as menopausal status, tumor size, lymph node, metastasis, grade, stage, estrogen receptor status, progesterone receptor status and her2/neu gene expression status. Similarly, the multivariate analysis also revealed that tumor subgroup was a significant factor related to 10-year breast cancer death-specific survival and disease-free survival, in addition to tumor size, lymph node, metastasis and grade. It was suggested that triple-negative breast cancer patients in Taiwan have worse 10-year survival. Notably, in node-positive patients, triple-negative breast cancer played a prognostic role in 10-year breast cancer death-specific survival.
Relation: Japanese Journal of Clinical Oncology
Appears in Collections:[中興大學] 期刊論文

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